Impact of reducing complement inhibitor binding on the immunogenicity of native neisseria meningitidis outer membrane vesicles
Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have investigated whether such complement inhibitor binding occurs after vaccination with native outer membrane vesicles (nOMVs), and limits immuno...
| Main Authors: | , , , , , , , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
Public Library of Science
2016
|