Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype

Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype

Activation of cardiac fibroblasts and differentiation to myofibroblasts underlies development of pathological cardiac fibrosis, leading to arrhythmias and heart failure. Myofibroblasts are characterised by increased α-smooth muscle actin (α-SMA) fibre expression, secretion of collagens and changes i...

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Autors principals:	Hall, C, Law, JP, Reyat, JS, Cumberland, MJ, Hang, S, Vo, NTN, Raniga, K, Weston, CJ, O'Shea, C, Townend, JN, Gehmlich, K, Ferro, CJ, Denning, C, Pavlovic, D
Format:	Journal article
Idioma:	English
Publicat:	Springer Nature 2023

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