Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype
Activation of cardiac fibroblasts and differentiation to myofibroblasts underlies development of pathological cardiac fibrosis, leading to arrhythmias and heart failure. Myofibroblasts are characterised by increased α-smooth muscle actin (α-SMA) fibre expression, secretion of collagens and changes i...
Հիմնական հեղինակներ: | Hall, C, Law, JP, Reyat, JS, Cumberland, MJ, Hang, S, Vo, NTN, Raniga, K, Weston, CJ, O'Shea, C, Townend, JN, Gehmlich, K, Ferro, CJ, Denning, C, Pavlovic, D |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Springer Nature
2023
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