High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.

Hypoxia-inducible factor (HIF) regulates the major transcriptional cascade central to the response of all mammalian cells to alterations in oxygen tension. Expression arrays indicate that many hundreds of genes are regulated by this pathway, controlling diverse processes that in turn orchestrate bot...

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Autors principals: Schödel, J, Oikonomopoulos, S, Ragoussis, J, Pugh, C, Ratcliffe, P, Mole, D
Format: Journal article
Idioma:English
Publicat: 2011