High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.

Hypoxia-inducible factor (HIF) regulates the major transcriptional cascade central to the response of all mammalian cells to alterations in oxygen tension. Expression arrays indicate that many hundreds of genes are regulated by this pathway, controlling diverse processes that in turn orchestrate bot...

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Bibliografische gegevens
Hoofdauteurs: Schödel, J, Oikonomopoulos, S, Ragoussis, J, Pugh, C, Ratcliffe, P, Mole, D
Formaat: Journal article
Taal:English
Gepubliceerd in: 2011