Intramolecular oxonium ylide formation-[2,3] sigmatropic rearrangement of diazocarbonyl-substituted cyclic unsaturated acetals: a formal synthesis of hyperolactone C.
Rh(II)-catalyzed oxonium ylide formation-[2,3] sigmatropic rearrangement of α-diazo-β-ketoesters possessing γ-cyclic unsaturated acetal substitution, followed by acid-catalyzed elimination-lactonization, provides a concise approach to 1,7-dioxaspiro[4.4]non-2-ene-4,6-diones. The process creates adja...
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Bibliographic Details
Main Authors: |
Hodgson, D,
Man, S,
Powell, K,
Perko, Z,
Zeng, M,
Moreno-Clavijo, E,
Thompson, A,
Moore, MD |
Format: | Journal article
|
Language: | English |
Published: |
American Chemical Society
2014
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