Quantitative variation in plasma angiotensin-i converting enzyme activity shows allelic heterogeneity in the ABO blood group locus

Angiotensin-I converting enzyme (ACE) occupies a pivotal role in cardiovascular homeostasis. Major loci for plasma ACE have been identified at ACE on Chromosome 17 and at ABO on Chromosome 9. We sought to characterise the genetic architecture of plasma ACE at finer resolution in two populations. We...

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Detalhes bibliográficos
Principais autores: Terao, C, Bayoumi, N, McKenzie, C, Zelenika, D, Muro, S, Mishima, M, Connell, J, Vickers, M, Mark Lathrop, G, Farrall, M, Matsuda, F, Keavney, B
Formato: Journal article
Idioma:English
Publicado em: 2013