The C-terminal of rat 4-hydroxyphenylpyruvate dioxygenase is indispensable for enzyme activity

The C-terminal of rat 4-hydroxyphenylpyruvate dioxygenase is indispensable for enzyme activity

<p>We have cloned and overexpressed rat 4-hydroxyphenylpyruvate dioxygenase (4HPPD) in <em>Escherichia coli</em>. The soluble, active recombinant enzyme was shown to contain both 4HPPD and α-ketoisocaproate dioxygenase (αKICD) activity. However, upon truncation of the 14 amino acid...

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Bibliografiske detaljer
Main Authors:	Lee, M, Zhang, Z, MacKinnon, C, Baldwin, J, Crouch, N
Andre forfattere:	Federation of European Biochemical Societies
Format:	Journal article
Sprog:	English
Udgivet:	Elsevier 1996
Fag:	Biochemistry

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