A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
Glucagon, secreted from pancreatic islet alpha cells, stimulates gluconeogenesis and liver glycogen breakdown. The mechanism regulating glucagon release is debated, and variously attributed to neuronal control, paracrine control by neighbouring beta cells, or to an intrinsic glucose sensing by the a...
Main Authors: | MacDonald, P, De Marinis, Y, Ramracheya, R, Salehi, A, Ma, X, Johnson, P, Cox, R, Eliasson, L, Rorsman, P |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
2007
|
Lignende værker
-
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
af: Macdonald, P, et al.
Udgivet: (2007) -
A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
af: Patrick E MacDonald, et al.
Udgivet: (2007-06-01) -
Effects of glucose, GLP-1 and adrenaline on alpha cell electrical activity and glucagon secretion from mouse pancreatic islets
af: Zhang, Q, et al.
Udgivet: (2010) -
Effects of GLP-1(9-36) and exendin-4 on glucagon secretion from human islets of Langerhans: evidence of a novel GLP-1 receptor in islets?
af: Ramracheya, R, et al.
Udgivet: (2014) -
KATP channel-dependent regulation of glucagon release from mouse and human pancreatic alpha-cells
af: Rorsman, P, et al.
Udgivet: (2007)