A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

Hiển thị phiên bản (1) khác

Glucagon, secreted from pancreatic islet alpha cells, stimulates gluconeogenesis and liver glycogen breakdown. The mechanism regulating glucagon release is debated, and variously attributed to neuronal control, paracrine control by neighbouring beta cells, or to an intrinsic glucose sensing by the a...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	MacDonald, P, De Marinis, Y, Ramracheya, R, Salehi, A, Ma, X, Johnson, P, Cox, R, Eliasson, L, Rorsman, P
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2007

Những quyển sách tương tự

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans
Bằng: Macdonald, P, et al.
Được phát hành: (2007)

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.
Bằng: Patrick E MacDonald, et al.
Được phát hành: (2007-06-01)

Effects of glucose, GLP-1 and adrenaline on alpha cell electrical activity and glucagon secretion from mouse pancreatic islets
Bằng: Zhang, Q, et al.
Được phát hành: (2010)

Effects of GLP-1(9-36) and exendin-4 on glucagon secretion from human islets of Langerhans: evidence of a novel GLP-1 receptor in islets?
Bằng: Ramracheya, R, et al.
Được phát hành: (2014)

KATP channel-dependent regulation of glucagon release from mouse and human pancreatic alpha-cells
Bằng: Rorsman, P, et al.
Được phát hành: (2007)

K(ATP)-channels and glucose-regulated glucagon secretion.
Bằng: Rorsman, P, et al.
Được phát hành: (2008)

Capacitance measurements of exocytosis in mouse pancreatic alpha-, beta- and delta-cells within intact islets of Langerhans.
Bằng: Göpel, S, et al.
Được phát hành: (2004)

Dual effects of low and high concentrations of cAMP on glucagon secretion from mouse pancreatic A-cells
Bằng: Eliasson, L, et al.
Được phát hành: (2009)

Electrophysiology of pancreatic β-cells in intact mouse islets of Langerhans.
Bằng: Rorsman, P, et al.
Được phát hành: (2011)

Regulation of glucagon secretion by glucose: paracrine, intrinsic or both?
Bằng: Walker, J, et al.
Được phát hành: (2011)

Evidence from in situ human alpha-cells supporting intrinsic K-ATP channel-dependent regulation of glucagon secretion
Bằng: Macdonald, P, et al.
Được phát hành: (2006)

Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.
Bằng: Ramracheya, R, et al.
Được phát hành: (2010)

Identification and characterization of single glucagon-secreting A-cells in a standard mouse islet preparation
Bằng: Barg, S, et al.
Được phát hành: (1999)

Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon.
Bằng: Collins, S, et al.
Được phát hành: (2008)

Glucagon stimulates exocytosis in mouse and rat pancreatic alpha-cells by binding to glucagon receptors.
Bằng: Ma, X, et al.
Được phát hành: (2005)

An atlas and functional analysis of G-protein coupled receptors in human islets of Langerhans
Bằng: Amisten, S, et al.
Được phát hành: (2013)

Cell coupling in mouse pancreatic beta-cells measured in intact islets of Langerhans.
Bằng: Zhang, Q, et al.
Được phát hành: (2008)

ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells.
Bằng: Gromada, J, et al.
Được phát hành: (2004)

ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: Similar functions but reciprocal effects on secretion
Bằng: Rorsman, P, et al.
Được phát hành: (2014)

ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.
Bằng: Rorsman, P, et al.
Được phát hành: (2014)

CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
Bằng: Anna Edlund, et al.
Được phát hành: (2017-03-01)

Expression of GABA(A) receptor Cl- channels and glucose-dependent GABA release in human pancreatic islets
Bằng: Braun, M, et al.
Được phát hành: (2006)

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.
Bằng: Barg, S, et al.
Được phát hành: (2000)

Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.
Bằng: De Marinis, Y, et al.
Được phát hành: (2010)

Dysregulation of glucagon secretion by hyperglycemia-induced sodium-dependent reduction of ATP production
Bằng: Knudsen, JG, et al.
Được phát hành: (2018)

Exocytosis study of beta- and alpha-cells in intact pancreatic islets using capacitance measurement
Bằng: Zhang, Q, et al.
Được phát hành: (2004)

GLP-1 inhibits glucagon secretion from human alpha cells by a direct effect
Bằng: Ramracheya, R, et al.
Được phát hành: (2010)

Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.
Bằng: Ramracheya, R, et al.
Được phát hành: (2006)

Insulin prevents counter-regulatory glucagon secretion by stimulation of somatostatin release
Bằng: Rorsman, P, et al.
Được phát hành: (2013)

The glucagon-producing alpha cell: an electrophysiologically exceptional cell.
Bằng: Braun, M, et al.
Được phát hành: (2010)

K(ATP) channels and islet hormone secretion: new insights and controversies.
Bằng: Ashcroft, F, et al.
Được phát hành: (2013)

Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Bằng: Gromada, J, et al.
Được phát hành: (1998)

Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans
Bằng: Lena eEliasson, et al.
Được phát hành: (2014-07-01)

Glucose in glucagon release.
Bằng: Rorsman, P, et al.
Được phát hành: (1990)

Does the K-ATP channel participate in the regulation of glucagon secretion?
Bằng: Bokvist, K, et al.
Được phát hành: (1999)

Elevation of cAMP promotes an Epac2 dependent, L-type Ca2+-channel coupled, Ca2+-induced Ca2+ release in mouse alpha cells
Bằng: Zhang, Q, et al.
Được phát hành: (2014)

Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion.
Bằng: MacDonald, P, et al.
Được phát hành: (2011)

Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion
Bằng: MacDonald, P, et al.
Được phát hành: (2011)

Isolation of adult porcine islets of Langerhans.
Bằng: Toso, C, et al.
Được phát hành: (2000)

Transplantation or islets of Langerhans: new developments
Bằng: A Caulfield, et al.
Được phát hành: (2001-12-01)