Characterization of the E-cadherin/catenin complex in colorectal carcinoma cell lines.
The E-cadherin/catenin complex is a prime mediator of cell-cell adhesion. APC mutations can result in loss of beta-catenin downregulation and an accumulation of beta-catenin in the cell. Beta-CATENIN mutations can have a similar effect. The aim of this study was to investigate the effect of beta-CAT...
Main Authors: | El-Bahrawy, M, Poulsom, R, Rowan, A, Tomlinson, I, Alison, MR, Poulsom, SR |
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Format: | Journal article |
Language: | English |
Published: |
2004
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