Characterization of the E-cadherin/catenin complex in colorectal carcinoma cell lines.

The E-cadherin/catenin complex is a prime mediator of cell-cell adhesion. APC mutations can result in loss of beta-catenin downregulation and an accumulation of beta-catenin in the cell. Beta-CATENIN mutations can have a similar effect. The aim of this study was to investigate the effect of beta-CAT...

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Hlavní autoři: El-Bahrawy, M, Poulsom, R, Rowan, A, Tomlinson, I, Alison, MR, Poulsom, SR
Médium: Journal article
Jazyk:English
Vydáno: 2004