Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.

The early risk of recurrence after transient ischaemic attack (TIA) or minor stroke is high, ranging from 11% at 7 days in population-based studies, where patients are seen non-urgently, to 3% at 7 days in studies where patients are seen urgently in specialist services. In long-term (up to 10 years)...

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मुख्य लेखकों: Pendlebury, S, Rothwell, P
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2009
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author Pendlebury, S
Rothwell, P
author_facet Pendlebury, S
Rothwell, P
author_sort Pendlebury, S
collection OXFORD
description The early risk of recurrence after transient ischaemic attack (TIA) or minor stroke is high, ranging from 11% at 7 days in population-based studies, where patients are seen non-urgently, to 3% at 7 days in studies where patients are seen urgently in specialist services. In long-term (up to 10 years) studies of vascular risks after TIA and stroke, the risk of stroke is highest early after the event, and then falls, whereas the risk of coronary events is constant over the follow-up period at around 2% per year. In contrast to the early risk after TIA and stroke, the long-term risks are more dependent on the underlying vascular risk factors than the characteristics of the event itself. Stroke is also associated with an increased risk of dementia. Prevalence of post-stroke dementia varies between studies but is around 28% at 3 months in hospital-based studies where pre-stroke dementia was not excluded and 18% in hospital-based studies excluding pre-stroke dementia. Risk factors for post-stroke dementia include low education, prior or recurrent stroke, and older age. In conclusion, available data suggest that the risk of recurrent vascular events is considerable after TIA and stroke, even in the longer term, and that there is also a high risk of dementia after stroke. However, more studies are required to determine medium- and long-term outcomes in the current era of aggressive secondary preventive therapy.
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spelling oxford-uuid:df59dc69-9a2b-45ab-931f-bde831f58f6d2022-03-27T09:38:50ZRisk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:df59dc69-9a2b-45ab-931f-bde831f58f6dEnglishSymplectic Elements at Oxford2009Pendlebury, SRothwell, PThe early risk of recurrence after transient ischaemic attack (TIA) or minor stroke is high, ranging from 11% at 7 days in population-based studies, where patients are seen non-urgently, to 3% at 7 days in studies where patients are seen urgently in specialist services. In long-term (up to 10 years) studies of vascular risks after TIA and stroke, the risk of stroke is highest early after the event, and then falls, whereas the risk of coronary events is constant over the follow-up period at around 2% per year. In contrast to the early risk after TIA and stroke, the long-term risks are more dependent on the underlying vascular risk factors than the characteristics of the event itself. Stroke is also associated with an increased risk of dementia. Prevalence of post-stroke dementia varies between studies but is around 28% at 3 months in hospital-based studies where pre-stroke dementia was not excluded and 18% in hospital-based studies excluding pre-stroke dementia. Risk factors for post-stroke dementia include low education, prior or recurrent stroke, and older age. In conclusion, available data suggest that the risk of recurrent vascular events is considerable after TIA and stroke, even in the longer term, and that there is also a high risk of dementia after stroke. However, more studies are required to determine medium- and long-term outcomes in the current era of aggressive secondary preventive therapy.
spellingShingle Pendlebury, S
Rothwell, P
Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.
title Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.
title_full Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.
title_fullStr Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.
title_full_unstemmed Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.
title_short Risk of recurrent stroke, other vascular events and dementia after transient ischaemic attack and stroke.
title_sort risk of recurrent stroke other vascular events and dementia after transient ischaemic attack and stroke
work_keys_str_mv AT pendleburys riskofrecurrentstrokeothervasculareventsanddementiaaftertransientischaemicattackandstroke
AT rothwellp riskofrecurrentstrokeothervasculareventsanddementiaaftertransientischaemicattackandstroke