Position statement on ethics, equipoise and research on charged particle radiation therapy

The use of charged-particle radiation therapy (CPRT) is an increasingly important development in the treatment of cancer. One of the most pressing controversies about the use of this technology is whether randomised controlled trials are required before this form of treatment can be considered to be...

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Главные авторы: Sheehan, M, Timlin, C, Peach, K, Binik, A, Puthenparampil, W, Lodge, M, Kehoe, S, Brada, M, Burnet, N, Clarke, S, Crellin, A, Dunn, M, Fossati, P, Harris, S, Hocken, M, Hope, T, Ives, J, Kamada, T, London, A, Miller, R, Parker, M, Pijls-Johannesma, M, Savulescu, J, Short, S, Skene, L
Формат: Journal article
Язык:English
Опубликовано: BMJ Publishing Group 2014
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author Sheehan, M
Timlin, C
Peach, K
Binik, A
Puthenparampil, W
Lodge, M
Kehoe, S
Brada, M
Burnet, N
Clarke, S
Crellin, A
Dunn, M
Fossati, P
Harris, S
Hocken, M
Hope, T
Ives, J
Kamada, T
London, A
Miller, R
Parker, M
Pijls-Johannesma, M
Savulescu, J
Short, S
Skene, L
author_facet Sheehan, M
Timlin, C
Peach, K
Binik, A
Puthenparampil, W
Lodge, M
Kehoe, S
Brada, M
Burnet, N
Clarke, S
Crellin, A
Dunn, M
Fossati, P
Harris, S
Hocken, M
Hope, T
Ives, J
Kamada, T
London, A
Miller, R
Parker, M
Pijls-Johannesma, M
Savulescu, J
Short, S
Skene, L
author_sort Sheehan, M
collection OXFORD
description The use of charged-particle radiation therapy (CPRT) is an increasingly important development in the treatment of cancer. One of the most pressing controversies about the use of this technology is whether randomised controlled trials are required before this form of treatment can be considered to be the treatment of choice for a wide range of indications. Equipoise is the key ethical concept in determining which research studies are justied. However, there is a good deal of disagreement about how this concept is best understood and applied in the specic case of CPRT. This report is a position statement on these controversies that arises out of a workshop held at Wolfson College, Oxford in August 2011. The workshop brought together international leaders in the relevant elds (radiation oncology, medical physics, radiobiology, research ethics and methodology), including proponents on both sides of the debate, in order to make signicant progress on the ethical issues associated with CPRT research. This position statement provides an ethical platform for future research and should enable further work to be done in developing international coordinated programmes of research.
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spelling oxford-uuid:df67b6ff-99bf-49ee-ab99-2fef4d1aba042022-03-27T09:39:14ZPosition statement on ethics, equipoise and research on charged particle radiation therapyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:df67b6ff-99bf-49ee-ab99-2fef4d1aba04EnglishSymplectic Elements at OxfordBMJ Publishing Group2014Sheehan, MTimlin, CPeach, KBinik, APuthenparampil, WLodge, MKehoe, SBrada, MBurnet, NClarke, SCrellin, ADunn, MFossati, PHarris, SHocken, MHope, TIves, JKamada, TLondon, AMiller, RParker, MPijls-Johannesma, MSavulescu, JShort, SSkene, LThe use of charged-particle radiation therapy (CPRT) is an increasingly important development in the treatment of cancer. One of the most pressing controversies about the use of this technology is whether randomised controlled trials are required before this form of treatment can be considered to be the treatment of choice for a wide range of indications. Equipoise is the key ethical concept in determining which research studies are justied. However, there is a good deal of disagreement about how this concept is best understood and applied in the specic case of CPRT. This report is a position statement on these controversies that arises out of a workshop held at Wolfson College, Oxford in August 2011. The workshop brought together international leaders in the relevant elds (radiation oncology, medical physics, radiobiology, research ethics and methodology), including proponents on both sides of the debate, in order to make signicant progress on the ethical issues associated with CPRT research. This position statement provides an ethical platform for future research and should enable further work to be done in developing international coordinated programmes of research.
spellingShingle Sheehan, M
Timlin, C
Peach, K
Binik, A
Puthenparampil, W
Lodge, M
Kehoe, S
Brada, M
Burnet, N
Clarke, S
Crellin, A
Dunn, M
Fossati, P
Harris, S
Hocken, M
Hope, T
Ives, J
Kamada, T
London, A
Miller, R
Parker, M
Pijls-Johannesma, M
Savulescu, J
Short, S
Skene, L
Position statement on ethics, equipoise and research on charged particle radiation therapy
title Position statement on ethics, equipoise and research on charged particle radiation therapy
title_full Position statement on ethics, equipoise and research on charged particle radiation therapy
title_fullStr Position statement on ethics, equipoise and research on charged particle radiation therapy
title_full_unstemmed Position statement on ethics, equipoise and research on charged particle radiation therapy
title_short Position statement on ethics, equipoise and research on charged particle radiation therapy
title_sort position statement on ethics equipoise and research on charged particle radiation therapy
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