Ribozyme mediated down-regulation of thrombospondin receptor CD36 inhibits the growth of the human osteosarcoma cell line.

Ribozyme mediated down-regulation of thrombospondin receptor CD36 inhibits the growth of the human osteosarcoma cell line.

Thrombospondin-1 (TSP1) is known to possess tumor suppressor functions. In contradiction, TSP1 enhances the stromal vascularization and growth of certain cancers. A cell adhesion receptor, CD36, has been shown to interact with a ligand TSP1. We studied how CD36 affects the growth of the osteosarcoma...

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Detalles Bibliográficos
Autores principales: Yamazaki, H, Handa, A, Nishi, M, Tokunaga, T, Tomisawa, M, Hatanaka, H, Abe, Y, Kijima, H, Ueyama, Y, Nakamura, M
Formato: Journal article
Lenguaje:English
Publicado: 2004

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