Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS)
Autoantibodies to different subtypes of the voltage-gated calcium channel (VGCC) have been described in two very different neurological syndromes, the Lambert-Eaton myasthenic syndrome (LEMS) and amyotrophic lateral sclerosis (ALS). In this chapter we discuss the evidence supporting the role of anti...
| Príomhchruthaitheoirí: | , |
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| Formáid: | Journal article |
| Foilsithe / Cruthaithe: |
2013
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| _version_ | 1826300813094420480 |
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| author | Lang, B Maddison, P |
| author_facet | Lang, B Maddison, P |
| author_sort | Lang, B |
| collection | OXFORD |
| description | Autoantibodies to different subtypes of the voltage-gated calcium channel (VGCC) have been described in two very different neurological syndromes, the Lambert-Eaton myasthenic syndrome (LEMS) and amyotrophic lateral sclerosis (ALS). In this chapter we discuss the evidence supporting the role of anti-P/Q-type VGCC autoantibodies in the pathogenesis of LEMS but challenging the role of any VGCC autoantibodies in ALS. © 2014 Elsevier B.V. All rights reserved. |
| first_indexed | 2024-03-07T05:22:51Z |
| format | Journal article |
| id | oxford-uuid:df852d1e-ee90-4354-a2c6-a8d667ea22c6 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T05:22:51Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:df852d1e-ee90-4354-a2c6-a8d667ea22c62022-03-27T09:39:59ZAutoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS)Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:df852d1e-ee90-4354-a2c6-a8d667ea22c6Symplectic Elements at Oxford2013Lang, BMaddison, PAutoantibodies to different subtypes of the voltage-gated calcium channel (VGCC) have been described in two very different neurological syndromes, the Lambert-Eaton myasthenic syndrome (LEMS) and amyotrophic lateral sclerosis (ALS). In this chapter we discuss the evidence supporting the role of anti-P/Q-type VGCC autoantibodies in the pathogenesis of LEMS but challenging the role of any VGCC autoantibodies in ALS. © 2014 Elsevier B.V. All rights reserved. |
| spellingShingle | Lang, B Maddison, P Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS) |
| title | Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS) |
| title_full | Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS) |
| title_fullStr | Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS) |
| title_full_unstemmed | Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS) |
| title_short | Autoantibodies in the Lambert-Eaton Myasthenic Syndrome (LEMS) and Amyotrophic Lateral Sclerosis (ALS) |
| title_sort | autoantibodies in the lambert eaton myasthenic syndrome lems and amyotrophic lateral sclerosis als |
| work_keys_str_mv | AT langb autoantibodiesinthelamberteatonmyasthenicsyndromelemsandamyotrophiclateralsclerosisals AT maddisonp autoantibodiesinthelamberteatonmyasthenicsyndromelemsandamyotrophiclateralsclerosisals |