NKCC1 deficiency in forming hippocampal circuits triggers neurodevelopmental disorder: Role of BDNF-TrkB signalling

The time-sensitive GABA shift from excitatory to inhibitory is critical in early neural circuits development and depends upon developmentally regulated expression of cation-chloride cotransporters NKCC1 and KCC2. NKCC1, encoded by the SLC12A2 gene, regulates neuronal Cl− homeostasis by chloride impo...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Szymanski, J, Minichiello, L
Μορφή: Journal article
Γλώσσα:English
Έκδοση: MDPI 2022