Site-specific ADP-ribosylation of histone H2B in response to DNA 2 double strand breaks

Site-specific ADP-ribosylation of histone H2B in response to DNA 2 double strand breaks

ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the...

Полное описание

Библиографические подробности
Главные авторы:	Rakhimova, A, Ura, S, Hsu, D, Wang, H, Pears, C, Lakin, N
Формат:	Journal article
Опубликовано:	Nature Publishing Group 2017

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