A two-compartment mechanochemical model of the roles of transforming growth factor β and tissue tension in dermal wound healing

The repair of dermal tissue is a complex process of interconnected phenomena, where cellular, chemical and mechanical aspects all play a role, both in an autocrine and in a paracrine fashion. Recent experimental results have shown that transforming growth factor−β (TGFβ) and tissue mechanics play ro...

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Bibliographic Details
Main Authors: Murphy, K, Hall, C, Maini, P, McCue, S, McElwain, D
Format: Journal article
Published: 2011