Labelling of interleukin-2 (IL-2) with 123-iodine with retention of its capacity to bind to activated lymphocytes.
Human recombinant interleukin-2 (IL-2) was labelled with Iodine-123 using modified Bolton and Hunter method. Separation from free iodine was performed by gel filtration chromatography using a Sephadex G10 column. HPLC analysis of labelled IL-2 showed that 98% of TCA precipitable radioactivity eluted...
Main Authors: | Signore, A, Beverley, P, Parman, A, Negri, M, Pozzilli, P |
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Format: | Journal article |
Language: | English |
Published: |
1987
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