Increases in DNA lesions and the DNA damage indicator Gadd45 following transient cerebral ischemia.
Transient global or focal ischemia leads to the production of several types of lesions in the DNA backbone including alkali-labile sites, and both single-stranded (ss) and double-stranded (ds) breaks. The ds breaks result in high molecular weight fragments of 10-50 kbp that contain both 3'- and...
| Main Authors: | , , , , , , , |
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| Format: | Conference item |
| Published: |
1997
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