The long and the short of RNA maps.
The landscapes of mammalian genomes are characterized by complex patterns of intersecting and overlapping sense and antisense transcription, giving rise to large numbers of coding and non-protein-coding RNAs (ncRNAs). A recent report by Kapranov and colleagues(1) describes three potentially novel cl...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2007
|
_version_ | 1826300869984911360 |
---|---|
author | Ponjavic, J Ponting, C |
author_facet | Ponjavic, J Ponting, C |
author_sort | Ponjavic, J |
collection | OXFORD |
description | The landscapes of mammalian genomes are characterized by complex patterns of intersecting and overlapping sense and antisense transcription, giving rise to large numbers of coding and non-protein-coding RNAs (ncRNAs). A recent report by Kapranov and colleagues(1) describes three potentially novel classes of RNAs located at the very edges of protein-coding genes. The presence of RNAs from one of these classes appears to be correlated with the expression levels of their associated genes. These results suggest that a proportion of these RNAs might have roles in the cis-regulation of neighbouring protein-coding genes' expression. |
first_indexed | 2024-03-07T05:23:42Z |
format | Journal article |
id | oxford-uuid:dfd01a7f-7531-4153-90f0-3d72571ae369 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T05:23:42Z |
publishDate | 2007 |
record_format | dspace |
spelling | oxford-uuid:dfd01a7f-7531-4153-90f0-3d72571ae3692022-03-27T09:42:05ZThe long and the short of RNA maps.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:dfd01a7f-7531-4153-90f0-3d72571ae369EnglishSymplectic Elements at Oxford2007Ponjavic, JPonting, CThe landscapes of mammalian genomes are characterized by complex patterns of intersecting and overlapping sense and antisense transcription, giving rise to large numbers of coding and non-protein-coding RNAs (ncRNAs). A recent report by Kapranov and colleagues(1) describes three potentially novel classes of RNAs located at the very edges of protein-coding genes. The presence of RNAs from one of these classes appears to be correlated with the expression levels of their associated genes. These results suggest that a proportion of these RNAs might have roles in the cis-regulation of neighbouring protein-coding genes' expression. |
spellingShingle | Ponjavic, J Ponting, C The long and the short of RNA maps. |
title | The long and the short of RNA maps. |
title_full | The long and the short of RNA maps. |
title_fullStr | The long and the short of RNA maps. |
title_full_unstemmed | The long and the short of RNA maps. |
title_short | The long and the short of RNA maps. |
title_sort | long and the short of rna maps |
work_keys_str_mv | AT ponjavicj thelongandtheshortofrnamaps AT pontingc thelongandtheshortofrnamaps AT ponjavicj longandtheshortofrnamaps AT pontingc longandtheshortofrnamaps |