Fevipiprant, a selective prostaglandin D-2 receptor 2 antagonist, potently inhibits chemotaxis and cytokine production by group 2 innate lymphoid cells

Fevipiprant, a selective prostaglandin D-2 receptor 2 antagonist, potently inhibits chemotaxis and cytokine production by group 2 innate lymphoid cells

Manylion Llyfryddiaeth
Prif Awduron:	Xue, L, Hardman, C, Chen, W, Batty, P, Ogg, G, Erpenbeck, V, Sandham, D
Fformat:	Conference item
Cyhoeddwyd:	American Thoracic Society 2018

Eitemau Tebyg

Fevipiprant inhibits prostaglandin D2 mediated activation of group 2 innate lymphoid cells (ILC2s)
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Cyhoeddwyd: (2018)

Fevipiprant inhibits prostaglandin D2 mediated activation of group 2 innate lymphoid cells (ILC2s)
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Cyhoeddwyd: (2019)

Fevipiprant, a selective prostaglandin D2 receptor 2 antagonist, inhibits human group 2 innate lymphoid cell aggregation and function
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Cyhoeddwyd: (2019)

Fevipiprant, a selective prostaglandin D(2)receptor 2 antagonist, potently inhibits chemotaxis and cytokine production by Tc2 cells (type-2 CD8(+)lymphocytes)
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Data on the oral CRTh2 antagonist QAW039 (fevipiprant) in patients with uncontrolled allergic asthma
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Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production
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Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production
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Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
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Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells.
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Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial
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Cytometric gating stringency impacts on studies of type 2 innate lymphoid cells in asthma
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CD1a presentation of endogenous antigens by group 2 innate lymphoid cells
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IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent
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Fully human antagonistic antibodies against CCR4 potently inhibit cell signaling and chemotaxis.
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Fevipiprant reduced airway smooth muscle massin asthmatics via PGD2Receptor antagonism
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Fevipiprant reduces airway smooth muscle mass in asthmatics via PGD2 receptor antagonism
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Cysteinyl leukotriene E4 activates human ILC2s and enhances the effect of prostaglandin D2 and epithelial cytokines
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The roles of type 2 cytotoxic T cells in inflammation, tissue remodeling, and prostaglandin (PG) D2 production are attenuated by PGD2 receptor 2 antagonism
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Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2.
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Dendritic Cell Vaccines Impact the Type 2 Innate Lymphoid Cell Population and Their Cytokine Generation in Mice
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Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis
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Group 2 Innate Lymphoid Cells in Allergic Rhinitis
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Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs
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Female and male mouse lung group 2 innate lymphoid cells differ in gene expression profiles and cytokine production.
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