Upregulation of indoleamine 2,3-dioxygenase in hepatitis C virus infection.

Upregulation of indoleamine 2,3-dioxygenase in hepatitis C virus infection.

Indoleamine 2,3-dioxygenase (IDO) is induced by proinflammatory cytokines and by CTLA-4-expressing T cells and constitutes an important mediator of peripheral immune tolerance. In chronic hepatitis C, we found upregulation of IDO expression in the liver and an increased serum kynurenine/tryptophan r...

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Hlavní autoři: Larrea, E, Riezu-Boj, J, Gil-Guerrero, L, Casares, N, Aldabe, R, Sarobe, P, Civeira, M, Heeney, J, Rollier, C, Verstrepen, B, Wakita, T, Borrás-Cuesta, F, Lasarte, J, Prieto, J
Médium: Journal article
Jazyk:English
Vydáno: 2007

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