Upregulation of indoleamine 2,3-dioxygenase in hepatitis C virus infection.
Indoleamine 2,3-dioxygenase (IDO) is induced by proinflammatory cytokines and by CTLA-4-expressing T cells and constitutes an important mediator of peripheral immune tolerance. In chronic hepatitis C, we found upregulation of IDO expression in the liver and an increased serum kynurenine/tryptophan r...
| Główni autorzy: | , , , , , , , , , , , , , |
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| Format: | Journal article |
| Język: | English |
| Wydane: |
2007
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