Modulation of proteolysis counteracts oxidative stress but impairs base excision repair in ATM-depleted cells

<p>Ataxia-telangiectasia (A-T), also known as Louis-Bar syndrome, is a neurodegenerative autosomal recessive disease caused by bi-allelic mutations in the ataxia-telangiectasia mutated (ATM) gene. The product of the ATM gene is a serine/threonine kinase that acts as primary mediator of cellula...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Yang, D
অন্যান্য লেখক: Dianov, G
বিন্যাস: গবেষণাপত্র
প্রকাশিত: 2017