Modulation of proteolysis counteracts oxidative stress but impairs base excision repair in ATM-depleted cells
<p>Ataxia-telangiectasia (A-T), also known as Louis-Bar syndrome, is a neurodegenerative autosomal recessive disease caused by bi-allelic mutations in the ataxia-telangiectasia mutated (ATM) gene. The product of the ATM gene is a serine/threonine kinase that acts as primary mediator of cellula...
| מחבר ראשי: | |
|---|---|
| מחברים אחרים: | |
| פורמט: | Thesis |
| יצא לאור: |
2017
|