Modulation of proteolysis counteracts oxidative stress but impairs base excision repair in ATM-depleted cells

<p>Ataxia-telangiectasia (A-T), also known as Louis-Bar syndrome, is a neurodegenerative autosomal recessive disease caused by bi-allelic mutations in the ataxia-telangiectasia mutated (ATM) gene. The product of the ATM gene is a serine/threonine kinase that acts as primary mediator of cellula...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक: Yang, D
अन्य लेखक: Dianov, G
स्वरूप: थीसिस
प्रकाशित: 2017