Divergent memory responses driven by adenoviral vectors are impacted by epitope competition

Adenoviral vectors induce robust epitope-specific CD8+ T cell responses. Within the repertoire of responses generated both conventional memory evolution and the phenomenon of memory inflation are seen. The rules governing which epitopes inflate are not fully known, but may include a role for both an...

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Détails bibliographiques
Auteurs principaux: Colston, J, Hutchings, C, Chinnakannan, S, Highton, A, Perez-Shibayama, C, Ludewig, B, Klenerman, P
Format: Journal article
Langue:English
Publié: Wiley 2019

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