CTLA-4 expression on antigen-specific cells but not IL-10 secretion is required for oral tolerance.
CD4(+) T cells play a vital role in mediating the tolerance induced at mucosal sites following exposure to non-pathogenic stimuli, and further understanding of the precise mechanisms by which these cells prevent aberrant responses is required. We have developed a model using transfer of DO11.10 TCR-...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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