Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.

Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.

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Eukaryotic protein kinases are generally classified as being either tyrosine or serine-threonine specific. Though not evident from inspection of their primary sequences, many serine-threonine kinases display a significant preference for serine or threonine as the phosphoacceptor residue. Here we sho...

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Hlavní autoři: Chen, C, Ha, B, Thévenin, A, Lou, H, Zhang, R, Yip, K, Peterson, JR, Gerstein, M, Kim, P, Filippakopoulos, P, Knapp, S, Boggon, T, Turk, B
Médium: Journal article
Jazyk:English
Vydáno: 2014

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