Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity.
Eukaryotic protein kinases are generally classified as being either tyrosine or serine-threonine specific. Though not evident from inspection of their primary sequences, many serine-threonine kinases display a significant preference for serine or threonine as the phosphoacceptor residue. Here we sho...
Principais autores: | Chen, C, Ha, B, Thévenin, A, Lou, H, Zhang, R, Yip, K, Peterson, JR, Gerstein, M, Kim, P, Filippakopoulos, P, Knapp, S, Boggon, T, Turk, B |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2014
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