T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system
Genome-wide association studies have identified noncoding variants near TBX3 that are associated with PR interval and QRS duration, suggesting that subtle changes in TBX3 expression affect atrioventricular conduction system function. To explore whether and to what extent the atrioventricular conduct...
Κύριοι συγγραφείς: | Mohan, RA, Bosada, FM, van Weerd, JH, van Duijvenboden, K, Wang, J, Mommersteeg, MTM, Hooijkaas, IB, Wakker, V, de Gier-de Vries, C, Coronel, R, Boink, GJJ, Bakkers, J, Barnett, P, Boukens, BJ, Christoffels, VM |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
National Academy of Sciences
2020
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system.
ανά: Bakker, M, κ.ά.
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Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction
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Developmental origin, growth, and three-dimensional architecture of the atrioventricular conduction axis of the mouse heart.
ανά: Aanhaanen, W, κ.ά.
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Embryonic Tbx3+ cardiomyocytes form the mature cardiac conduction system by progressive fate restriction
ανά: Mohan, R, κ.ά.
Έκδοση: (2018) -
Role of Genetic Variation in Transcriptional Regulatory Elements in Heart Rhythm
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