Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.

The purpose of this study was to provide a statistical description of the breath-to-breath variations in ventilation during steady breathing in both rest and during light exercise, with the end-tidal gases controlled by using an end-tidal forcing system. Sixty data sets were studied, only one of whi...

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Opis bibliograficzny
Główni autorzy: Liang, P, Pandit, J, Robbins, P
Format: Journal article
Język:English
Wydane: 1996
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author Liang, P
Pandit, J
Robbins, P
author_facet Liang, P
Pandit, J
Robbins, P
author_sort Liang, P
collection OXFORD
description The purpose of this study was to provide a statistical description of the breath-to-breath variations in ventilation during steady breathing in both rest and during light exercise, with the end-tidal gases controlled by using an end-tidal forcing system. Sixty data sets were studied, only one of which was white (i.e., did not show autocorrelation). Three simple autoregressive moving average (ARMA) models, i.e., AR1, AR2, and AR1MA1, and one simple state-space model were fitted to the data and resulted in white residuals in 15, 31, 46, and 48 out of 60 occasions, respectively. Evolutionary spectral analysis revealed that only 13 data sets had a constant power spectrum, although 50 were uniformly modulated. An autoregressive estimate of variance could be used to "demodulate" the data in most cases, but the results were not significantly affected by fitting the model to the demodulated data. The results indicate that 1) both simple ARMA models and a simple state-space model can describe the autocorrelation present; 2) variations in spectral power were present in the data that cannot be described by these models; and 3) these variations were often due to a uniform modulation and did not significantly affect the coefficients for the models. For these kinds of data, a heteroscedastic form of state-space model provides an attractive theoretical structure for the noise processes.
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spelling oxford-uuid:e0554ab2-808f-429d-8482-c7d9658d72792022-03-27T09:46:26ZStatistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e0554ab2-808f-429d-8482-c7d9658d7279EnglishSymplectic Elements at Oxford1996Liang, PPandit, JRobbins, PThe purpose of this study was to provide a statistical description of the breath-to-breath variations in ventilation during steady breathing in both rest and during light exercise, with the end-tidal gases controlled by using an end-tidal forcing system. Sixty data sets were studied, only one of which was white (i.e., did not show autocorrelation). Three simple autoregressive moving average (ARMA) models, i.e., AR1, AR2, and AR1MA1, and one simple state-space model were fitted to the data and resulted in white residuals in 15, 31, 46, and 48 out of 60 occasions, respectively. Evolutionary spectral analysis revealed that only 13 data sets had a constant power spectrum, although 50 were uniformly modulated. An autoregressive estimate of variance could be used to "demodulate" the data in most cases, but the results were not significantly affected by fitting the model to the demodulated data. The results indicate that 1) both simple ARMA models and a simple state-space model can describe the autocorrelation present; 2) variations in spectral power were present in the data that cannot be described by these models; and 3) these variations were often due to a uniform modulation and did not significantly affect the coefficients for the models. For these kinds of data, a heteroscedastic form of state-space model provides an attractive theoretical structure for the noise processes.
spellingShingle Liang, P
Pandit, J
Robbins, P
Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.
title Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.
title_full Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.
title_fullStr Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.
title_full_unstemmed Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.
title_short Statistical properties of breath-to-breath variations in ventilation at constant PETCO2 and PETO2 in humans.
title_sort statistical properties of breath to breath variations in ventilation at constant petco2 and peto2 in humans
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