Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.

Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.

ग्रंथसूची विवरण
मुख्य लेखकों: Schlemminger, I, Mole, D, McNeill, L, Dhanda, A, Hewitson, K, Tian, Y, Ratcliffe, P, Pugh, C, Schofield, C
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2003
विवरण
सारांश:Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.