Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.
Những tác giả chính: | Schlemminger, I, Mole, D, McNeill, L, Dhanda, A, Hewitson, K, Tian, Y, Ratcliffe, P, Pugh, C, Schofield, C |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2003
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