Analogues of dealanylalahopcin are inhibitors of human HIF prolyl hydroxylases.
Analogues of the naturally occurring cyclic hydroxamate dealanylalahopcin, which is an inhibitor of procollagen prolyl-4-hydroxylase, were synthesised and shown to be inhibitors of the human hypoxia-inducible factor prolyl hydroxylases.
Autori principali: | , , , , , , , , |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2003
|