Addition of senna improves quality of colonoscopy preparation with magnesium citrate.
AIM: To prospectively investigate the effectiveness and patient's tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS: A total of 342 patients who were referred for colonoscopy underwent a col...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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| _version_ | 1797099562512416768 |
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| author | Vradelis, S Kalaitzakis, E Sharifi, Y Buchel, O Keshav, S Chapman, R Braden, B |
| author_facet | Vradelis, S Kalaitzakis, E Sharifi, Y Buchel, O Keshav, S Chapman, R Braden, B |
| author_sort | Vradelis, S |
| collection | OXFORD |
| description | AIM: To prospectively investigate the effectiveness and patient's tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS: A total of 342 patients who were referred for colonoscopy underwent a colon cleansing protocol with magnesium citrate alone (n = 160) or magnesium citrate and senna granules (n = 182). The colonoscopist rated the overall efficacy of colon cleansing using an established score on a 4-point scale. Patients were questioned before undergoing colonoscopy for side effects and symptoms during bowel preparation. RESULTS: The percentage of procedures rescheduled because of insufficient colon cleansing was 7% in the magnesium citrate group and 4% in the magnesium citrate/senna group (P = 0.44). Adequate visualization of the colonic mucosa was rated superior under the citramag/senna regimen (P = 0.004). Both regimens were well tolerated, and did not significantly differ in the occurrence of nausea, bloating or headache. However, abdominal cramps were observed more often under the senna protocol (29.2%) compared to the magnesium citrate only protocol (9.9%, P < 0.0003). CONCLUSION: The addition of senna to the bowel preparation protocol with magnesium citrate significantly improves the cleansing outcome. |
| first_indexed | 2024-03-07T05:25:33Z |
| format | Journal article |
| id | oxford-uuid:e06c4bcb-3c36-4f6d-8811-9885f5a76c41 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:25:33Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:e06c4bcb-3c36-4f6d-8811-9885f5a76c412022-03-27T09:47:04ZAddition of senna improves quality of colonoscopy preparation with magnesium citrate.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e06c4bcb-3c36-4f6d-8811-9885f5a76c41EnglishSymplectic Elements at Oxford2009Vradelis, SKalaitzakis, ESharifi, YBuchel, OKeshav, SChapman, RBraden, BAIM: To prospectively investigate the effectiveness and patient's tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS: A total of 342 patients who were referred for colonoscopy underwent a colon cleansing protocol with magnesium citrate alone (n = 160) or magnesium citrate and senna granules (n = 182). The colonoscopist rated the overall efficacy of colon cleansing using an established score on a 4-point scale. Patients were questioned before undergoing colonoscopy for side effects and symptoms during bowel preparation. RESULTS: The percentage of procedures rescheduled because of insufficient colon cleansing was 7% in the magnesium citrate group and 4% in the magnesium citrate/senna group (P = 0.44). Adequate visualization of the colonic mucosa was rated superior under the citramag/senna regimen (P = 0.004). Both regimens were well tolerated, and did not significantly differ in the occurrence of nausea, bloating or headache. However, abdominal cramps were observed more often under the senna protocol (29.2%) compared to the magnesium citrate only protocol (9.9%, P < 0.0003). CONCLUSION: The addition of senna to the bowel preparation protocol with magnesium citrate significantly improves the cleansing outcome. |
| spellingShingle | Vradelis, S Kalaitzakis, E Sharifi, Y Buchel, O Keshav, S Chapman, R Braden, B Addition of senna improves quality of colonoscopy preparation with magnesium citrate. |
| title | Addition of senna improves quality of colonoscopy preparation with magnesium citrate. |
| title_full | Addition of senna improves quality of colonoscopy preparation with magnesium citrate. |
| title_fullStr | Addition of senna improves quality of colonoscopy preparation with magnesium citrate. |
| title_full_unstemmed | Addition of senna improves quality of colonoscopy preparation with magnesium citrate. |
| title_short | Addition of senna improves quality of colonoscopy preparation with magnesium citrate. |
| title_sort | addition of senna improves quality of colonoscopy preparation with magnesium citrate |
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