Specialized transcription factories within mammalian nuclei.
Recent evidence suggests that active RNA polymerases are concentrated in discrete 'factories' where they work together on many different templates. The evidence that such factories specialize in the transcription of particular groups of genes is reviewed.
Main Authors: | Pombo, A, Jones, E, Iborra, F, Kimura, H, Sugaya, K, Cook, P, Jackson, D |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2000
|
Similar Items
Similar Items
-
Active RNA polymerases are localized within discrete transcription "factories' in human nuclei.
by: Iborra, F, et al.
Published: (1996) -
Coupled transcription and translation within nuclei of mammalian cells.
by: Iborra, F, et al.
Published: (2001) -
Nuclear factories for replication, transcription and repair
by: McManus, J, et al.
Published: (1995) -
Transcription factories and chromosome structure
by: Pombo, A, et al.
Published: (1997) -
Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei.
by: Jackson, D, et al.
Published: (1998)