Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging.
We report development of the first genetically encoded bioluminescent indicator for membrane voltage called LOTUS-V. Since it is bioluminescent, imaging LOTUS-V does not require external light illumination. This allows bidirectional optogenetic control of cellular activity triggered by Channelrhodop...
Main Authors: | Inagaki, S, Tsutsui, H, Suzuki, K, Agetsuma, M, Arai, Y, Jinno, Y, Bai, G, Daniels, M, Okamura, Y, Matsuda, T, Nagai, T |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Nature Publishing Group
2017
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