Triazole carboxylic acids as anionic sugar mimics? Inhibition of glycogen phosphorylase by a D-glucotriazole carboxylate

Triazole-carboxylic acids related to D-glucose and D-galactose may be prepared by intramolecular [1,3]-dipolar cycloadditions of azides to unsaturated esters, followed by bromine oxidation of the resulting triazoline. Such materials may provide a series of anionic mimics of carbohydrates.

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ: Krulle, T, delaFuente, C, Pickering, L, Aplin, RT, Tsitsanou, K, Zographos, SE, Oikonomakos, N, Nash, R, Griffiths, R, Fleet, G
Ձևաչափ: Journal article
Լեզու:English
Հրապարակվել է: 1997