Targeting the hedgehog pathway in disease: a structural biology approach

<p>The Hedgehog (Hh) pathway is a morphogen pathway essential for proper embryonic development of all bilaterians that remains active in adults where it contributes to tissue homoeostasis. Malfunction of the pathway results in developmental defect, while constitutive activation was correla...

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Détails bibliographiques
Auteur principal: Sefer, L
Autres auteurs: Siebold, C
Format: Thèse
Publié: 2017