Hyperinflammatory syndrome, natural killer cell function, and genetic polymorphisms in the pathogenesis of severe dengue

Background Severe dengue, characterized by shock and organ dysfunction, is driven by an excessive host immune response. We investigated the role of hyperinflammation in dengue pathogenesis. Methods Patients recruited into an observational study were divided into 3 plasma leak severity grades. Hyper...

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Hlavní autoři: Vuong, NL, Cheung, K-W, Periaswamy, B, Vi, TT, Duyen, HTL, Leong, YS, Binte Hamis, ZN, Gregorova, M, Ooi, EE, Sessions, O, Rivino, L, Yacoub, S
Médium: Journal article
Jazyk:English
Vydáno: Oxford University Press 2022