Hyperinflammatory syndrome, natural killer cell function, and genetic polymorphisms in the pathogenesis of severe dengue

Background Severe dengue, characterized by shock and organ dysfunction, is driven by an excessive host immune response. We investigated the role of hyperinflammation in dengue pathogenesis. Methods Patients recruited into an observational study were divided into 3 plasma leak severity grades. Hyper...

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Detalhes bibliográficos
Main Authors: Vuong, NL, Cheung, K-W, Periaswamy, B, Vi, TT, Duyen, HTL, Leong, YS, Binte Hamis, ZN, Gregorova, M, Ooi, EE, Sessions, O, Rivino, L, Yacoub, S
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2022