MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets.
Mucosal-associated invariant T (MAIT) cells are an innate-like T-cell population restricted by the non-polymorphic, major histocompatibility complex class I-related protein 1, MR1. MAIT cells are activated by a broad range of bacteria through detection of riboflavin metabolites bound by MR1, but the...
Main Authors: | Kurioka, A, Ussher, J, Cosgrove, C, Clough, C, Fergusson, JR, Smith, K, Kang, Y, Walker, L, Hansen, T, Willberg, C, Klenerman, P |
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格式: | Journal article |
语言: | English |
出版: |
Nature Publishing Group
2015
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