Ascending aortic stenosis selectively increases action potential-induced Ca2+ influx in epicardial myocytes of the rat left ventricle.

A decrease of the transient outward potassium current (Ito) has been observed in cardiac hypertrophy and contributes to the altered shape of the action potential (AP) of hypertrophied ventricular myocytes. Since the shape and duration of the ventricular AP are important determinants of the Ca2+ infl...

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Bibliographic Details
Main Authors: Volk, T, Noble, P, Wagner, M, Noble, D, Ehmke, H
Format: Journal article
Language:English
Published: 2005