The interplay between iron and oxygen homeostasis with a particular focus on the heart
Iron is subject to tight homeostatic control in mammals. At the systemic level, iron homeostasis is controlled by the liver-derived hormone hepcidin acting on its target ferroportin in the gut, spleen and liver, which form the sites of iron uptake, recycling and storage, respectively. At the cellula...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
American Physiological Society
2017
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