Regulation of E2F-1 by methylation and NEDDylation

<p>E2F-1 has a central role in cell cycle orchestration, and its activity is tightly regulated. One of the ways E2F-1 activity is controlled is by direct modification by post translational modifications such as acetylation, ubiquitination and phosphorylation. Here it was demonstrated that E2F-...

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Bibliographic Details
Main Authors: Loftus, S, Sarah Loftus
Other Authors: La Thangue, N
Format: Thesis
Language:English
Published: 2012
Subjects: