IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis.

Slični predmeti

• IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer.
  od: Gyrd-Hansen, M, i dr.
  Izdano: (2010)
• NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
  od: Smith, C, i dr.
  Izdano: (2001)
• A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB
  od: Li Yongming, i dr.
  Izdano: (2009-11-01)
• Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
  od: Andreakos, E, i dr.
  Izdano: (2006)
• Erratum: IAPs: From caspase inhibitors to modulators of NF-κB, inflammation and cancer (Nature Reviews Cancer (2010) 10 (561-574))
  od: Gyrd-Hansen, M, i dr.
  Izdano: (2010)