The activation of endothelin-1 pathway during methionine-induced homocysteinemia mediates endothelial dysfunction in hypertensive individuals.
OBJECTIVES: Endothelin-1 (ET-1) is a key regulator of arterial blood pressure in humans, and homocysteinemia is associated with increased oxidative stress. It is still unclear whether homocysteine-induced oxidative stress is implicated in the regulation of ET-1 expression. We examined the impact of...
Автори: | Tousoulis, D, Bouras, G, Antoniades, C, Marinou, K, Miliou, A, Papageorgiou, N, Chatzis, G, Tentolouris, C, Tsioufis, C, Stefanadis, C |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2010
|
Схожі ресурси
Схожі ресурси
-
Methionine-induced homocysteinemia impairs endothelial function in hypertensives: the role of asymmetrical dimethylarginine and antioxidant vitamins.
за авторством: Tousoulis, D, та інші
Опубліковано: (2011) -
Methionine-loading rapidly impairs endothelial function, by mechanisms independent of endothelin-1: evidence for an association of fasting total homocysteine with plasma endothelin-1 levels.
за авторством: Tousoulis, D, та інші
Опубліковано: (2008) -
Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines.
за авторством: Antoniades, C, та інші
Опубліковано: (2006) -
Genetic variability on adiponectin gene affects myocardial infarction risk: the role of endothelial dysfunction.
за авторством: Antonopoulos, A, та інші
Опубліковано: (2013) -
Genetic variability on adiponectin gene affects myocardial infarction risk: The role of endothelial dysfunction
за авторством: Antonopoulos, A, та інші
Опубліковано: (2013)